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Reynolds CJ, Pade C, Gibbons JM, Otter AD, Lin KM, Muoz Sandoval D, et al

Cancer Lett (2006) 241(2):2217

SEB stimulated lymphocytes receiving Etomoxir treatment revealed 49%, 64% (p = 0.0037) and 44% downregulation of interferon- (IFN- ), interleukin-17 (IL-17 ) and tumor necrosis factor- (TNF- )

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This aspect could reflect an altered action of ghrelin on its specific receptors implicated in feedback mechanisms.83 Regarding the role of CCK in inhibiting food intake, CCK-A receptor knockout rats are hyperphagic and obese.84 In animals, as expected, repeated preprandial administration of CCK reduces food intake but it also increases meal frequency, with no resulting effect on body weight.85 Circulating levels of PYY are not elevated in obese individuals