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It also increased 4-hydroxynonenal levels and decreased GPX4 levels, which led to ferroptosis

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Clinical trials and user reports indicate that gastrointestinal disturbances, including burping, are relatively common among individuals taking this medication

However, this is expected, as the Italian Medicines Agency recently passed a decision to allow practitioners, as opposed to specialists only, in Italy to prescribe GLP-1 RAs to metformin-receiving patients [24]