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This hyperpolarizes the cell membrane, making it significantly harder for the neuron to fire an action potential

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Meanwhile, translating other promising preclinical findings, such as those involving BPC-157, to clinical practice requires thorough investigation to ensure safety and efficacy

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Considerations Slower onset: Because the peptide must traverse the nasal membranes and then enter general circulation (and eventually reach brain/central nervous system targets), the onset tends to be more gradual