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Mou et al., 2022

You mentioned tight junctions, and the way I think about tight junctions please correct me because Im going to get some or all of this wrong is that essentially they form like a cellular fence in the gut, and that transient opening or partial opening of these is a normal process

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Mice treated with both OIT and BF2 (12 mg/mouse per day) demonstrated significantly less severe and fewer adverse reactions than OIT-treated, alone [39]

Therefore, sustained investment in basic and translational research, coupled with robust interdisciplinary collaboration, will be pivotal in transforming ferroptosis modulation from a promising experimental concept into a clinically viable therapeutic paradigm for GBM