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Zgair A, Dawood Y, Ibrahem SM, Back H, Kagan L, Gershkovich P, Lee JB

Linn, J.G

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These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite

MST1 in the hippo pathways is also strongly activated in T2D, inducing cell apoptosis through activation of JNK and impairing cell function through destabilizing PDX1 144 (Fig