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It is to explain what they are, what the physiology suggests, what the evidence shows, and where the risks sit

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Merck is highly concentrated in Keytruda (~50% of sales), making its post-2028 growth hinge on successful oncology and cardiology pipeline execution

Clinical trial data from the STEP programme (semaglutide 2.4 mg) and SCALE studies (liraglutide 3 mg) demonstrates that weight loss follows a progressive pattern rather than occurring suddenly

Clinical trials show tirzepatide produces 20 to 25 percent greater weight loss than semaglutide alone in comparable populations