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Thus, the amount of LC3-II is correlated with the autophagy level and is a reliable marker for monitoring autophagy-related processes 21

Conventional therapy is largely about managing the crisis

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In the D-Gal + FOXO4-DRI group, mice also received D-galactose injections and, after 4 weeks, were given intraperitoneal injections of FOXO4-DRI (5 mg/kg, MCE, HY-P4157) every 2 days for 4 weeks, followed by tissue collection

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