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Copper-doped carbon dots (Cu-CDs) exploit this weakness by selectively targeting metallothionein-2 (MT-2), a key antioxidant protein

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while 7 of the 12 patients reported subjective pain relief exceeding six months, the complete absence of a placebo control group or standardized pain-scale methodology severely limits the scientific validity and reproducibility of the findings

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Fractals 30 , 2240051 (2022)