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Gastrointestinal AE with cagrisema were more than with semagutide or cagrilintide monotherapy, however the SAE and AE leading to medication discontinuation were minimal and similar between the groups [87, 90] A programme of phase 3 clinical trials (REDEFINE) assessing the safety and efficacy of cagrisema in people with obesity (NCT05567796, NCT05394519, NCT05813925) is currently ongoing
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Temporary adjustments in bowel movements, including mild diarrhea, constipation, or transient bloating
More research is needed to better understand how N-acetylcysteine can affect human health
8,262 This may be a contributing factor in the relationship between high homocysteine levels and psycho-emotional conditions such as depression, as well as the higher risk of depression seen in carriers of the MTHFR gene variant associated with impaired folate metabolism
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