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While traditional manufacturing processes using bioreactors and mammalian, bacterial or yeast cell cultures are well-established in the pharmaceutical sector, these platforms are expensive, and production can be hampered by human pathogen contamination

In addition, diabetic patients treated over a 30-56 week period experienced 4.5-6.5kg weight loss

Another area of focus has been the potential for an increased risk of certain types of cancers, particularly medullary thyroid carcinoma (MTC)

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Selection of internal references under disease or treatment conditions (1) Hypoxia, diabetic models, tumor tissues: increased GAPDH expression, unsuitable for use as an internal reference [7]