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It is a 37-residue C-terminally amidated peptide closed by a Cys2-Cys7 disulfide bridge, sequence KCNTATCATQRLAEFLRHSSNNFGPILPPTNVGSNTP-NH, with the Lys1 side chain acylated by a C20 fatty diacid through a gamma-glutamate linker

We have published several editorials (see below on this webpage) pointing out the obvious fallacy about the EPIC Study's baseless definition of heart enlargement in MVD-affected cavaliers and other breeds of dogs

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