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The native GHRH(129) fragment (sold as Mod GRF 1-29) is active but short-lived in circulation, with a plasma half-life of only a few minutes
Given the high unmet medical need, limited competition, and established efficacy in narcolepsy, WAKIX is expected to gain strong commercial traction and have an extended market uptake period if approved for PWS
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We believe that BDP-12, with its distinct TLR4-targeting strategy and its natural property, may be better accepted by the body, thus holding greater potential for clinical translation and drug development
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