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When both stimuli were present, the calculated response increased to about 54-fold above saline, which corresponds to a modest additional gain over GHRP-2 alone

Now compare this to the conversation around DTC elective whole-body MRIs

Each method has pros and cons

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Elevated cortisol directly inhibits GH receptor signaling in target tissues and increases hepatic GH resistance, meaning even if you achieve a GH pulse, downstream IGF-1 production and metabolic signaling are impaired