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doi:10.1007/s10815-013-0047-5

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Copper-Coordination Research Copper is a redox-active transition metal used by multiple enzymes and molecular systems

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Methylfolate provides the biologically active form without requiring DHFR conversion and may therefore be preferable where reduced enzyme activity is suspected

Populations with increased vulnerability pregnant women, neonates, the elderly, immunocompromised individuals, and occupationally exposed workers require particular consideration in risk assessment and mitigation strategies