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Il joue notamment un rle crucial dans la dfense de lorganisme, le mtabolisme des nutriments et la rgulation des diffrentes voies essentielles lquilibre gnral

ACSF was composed of 125 mM NaCl, 25 mM glucose, 25 mM NaHCO 3 , 2.5 mM KCl, 2 mM CaCl 2 , 1.25 mM NaH 2 PO 4 and 1 mM MgCl 2 that was saturated with 95% oxygen and 5% carbon dioxide and maintained at room temperature (2022 C)

The first two principal components explained 37.9% of the total variance (PC1 = 23%, PC2 = 14.9%) (Figure S2)

Mechanistically, TXNIP regulates the inactivation of mechanistic target of rapamycin kinase complex 1 (MTORC1), thereby promoting autophagy

W.2nd (2015)

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