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2022 May 28 [cited 2023 Apr 3];14(6):1152

Most patients begin at 0.25 mg weekly and increase gradually every 4 weeks under provider guidance, moving through dose escalations of 0.5 mg, 1 mg, and potentially 2.4 mg based on tolerance and results

Over-expression of the Sirt3 sirtuin protects neuronally differentiated PC12 Cells from degeneration induced by oxidative stress and trophic withdrawal

Appetite suppression can reduce food intake

These findings provide valuable insights into what happens when treatment ends and weight regain dynamics come into play