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The process of wound healing is intricate and cascaded, particularly in chronic wounds like severe burns and diabetic wounds, where unfavorable endogenous or external variables can impede the healing process by interfering with the regulation of inflammation [37]

In some cases, freezing can be more harmful than heat if the glutathione formulation contains emulsifiers or liposomes that degrade when frozen

[DOI] [PMC free article] [PubMed] [Google Scholar] Zou J., Wang J., Gao L., Xue W., Zhu J., Zhang Y., Gou S., Liu H., Zhong C., Ni J