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The dose was well tolerated by the subjects, and a decrease in parameters capturing oxidative stress, an increase in antioxidant capacity and an improvement in glycated hemoglobin (HbA1c) and renal metabolism (alpha-1 microglobulin) were observed [43]

Additionally, we excluded non-tonic formulations, specifically drugs that could not be dissolved in a tonic solvent composed of water and ethanol, such as CP21R7 and BIO

Chronic organ damage, particularly renal damage, may occur in patients with MMA

IFN- is produced mainly by nature killing (NK) cells and increases CD31 and vascular cell adhesion molecule (VCAM)-1, resulting in the expansion of innate immune cell infiltration (82)

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Blood Cells Mol Dis 2002