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Martn ED, Snchez-Perez A, Trejo JL, et al

Rarely clinically significant

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CHAC1 demonstrates higher catalytic efficiency and is upregulated during development or in response to stress

GLP-1R is present in the human choroid plexus, where GLP-1R analogs reduces cerebrospinal fluid secretion and intracranial pressure by increasing the intracellular concentration of cyclic adenosine monophosphate and inhibiting the Na + /K + ATPase pump in the choroid plexus [25]