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One is a soluble form found within the cytosol and is involved in the iron-mediated regulation of protein synthesis, specifically the translation of several mRNAs including the ferritin and the transferrin receptor mRNAs (see the Protein Synthesis (Translation): Processes and Regulation page)
ABCB11 (PFIC2) variants present an enhanced risk of developing liver cancers, as shown in the NAPPED study [15]
10.3390/ph16081121 101 PengM.DarkoK
Ferguson, G
Interestingly, knockdown of RIPK1 exacerbated ZEA-induced toxicity but did not diminish the protective effect of scutellarin, implying potential pathway redundancy or alternative mechanisms of action
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