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This dual-agonist mechanism distinguishes tirzepatide from single-pathway GLP-1 receptor agonists such as semaglutide

Tirzepatides long-term side effects affect around 5% of patients and include: Nausea Vomiting Diarrhea Decreased appetite Hair loss Dizziness Abdominal pain, indigestion 1 to 7% of people have an injection site reaction, such as itching or hives, but serious reactions are rare

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