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Site rotation, proper injection technique, and using appropriately sized needles minimize these occurrences

The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)

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The shots are particularly useful for individuals who feel low on energy or find it difficult to achieve their health targets

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