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The results established that low dose sodium selenite supplementation led to a significant increase in GPx activity and the corresponding mRNA levels of GPx isozymes such as GPx1 , GPx2 , and GPx4 in the radiosensitive organs (spleen and intestine of mice)
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It features a heterodifunctional molecule integrating two crucial ligands: one targeting and binding to the protein of interest, and another engaging with an E3 ligase, a pivotal element within the ubiquitin-proteasome system tasked with marking proteins for degradation (Zeng et al., 2021)
(1999) Direct interaction in T-cells between theta KC and the tyrosine kinase p59fyn