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On the one hand, four studies demonstrated that prenatal RSV treatment could reverse VPA-induced social deficits ( RSV prevented or ameliorated abnormalities in animal models of ASD through various molecular mechanisms, mainly anti-oxidative stress, and anti-inflammatory functions

References Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, et al

However, as the capacity of SDH-b continues to decline beyond a critical point, the compensatory mechanism of upregulating Complex I becomes insufficient

doi: 10.1371/journal.pone.0069327, 22

Zagrska A, Travs PG, Lew ED, Dransfield I, Lemke G

(Article in Japanese) Kuwasawa-Iwasaki M, Io H, Muto M, et al