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Diarrhea and constipation are also frequent, with each affecting 10 to 20 percent of individuals

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Table 5 Studies in experimental animals on the effects of the omega-3 polyunsaturated fatty acids (PUFA) in the thyroid setting

Subsequent efforts to identify the enzyme responsible for cGAMP production led to the characterization of cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor that directly binds double-stranded DNA and catalyzes cGAMP synthesis upon activation (Sun et al., 2013)

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