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The CREDENCE trial (Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation) also evaluated the cardiovascular risk reduction of canagliflozin, but in patients with type 2 diabetes and established chronic kidney disease

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Analyses of Pet1 knockout mice, in which most dorsal raphe neurons lacked 5-HT, revealed that 5-HT in the fetal forebrain was of placental and not maternal or fetal origin (131)

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Given the central role of microbiota in the persistence and recurrence of infections, there is a growing need for therapeutic platforms that not only offer Antimicrobial efficacy but also minimize toxicity and environmental burden

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