V., Rowan, M
The key words tirzepatide and Diabetes, tirzepatide and Obesity, novel antidiabetics were used to search the related articles
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The under-excretion of urates is the most frequent etiology (90% of cases) of hyperuricemia and it may be classified into primary conditions characterized by a decrease in the tubular secretion of urates, or into secondary conditions due to renal failure or other causes such as diabetes, alcoholic ketosis and lactic acidosis 2,7

[5] Adrenal tumor (most commonly pheochromocytoma) intratumoral bleeding [6] (Short-term) steroid usage [7] Trauma (mostly blunt trauma, can also occur postoperatively) [8] In neonates: birth trauma, difficult labor (e.g., breech delivery, forceps/vacuum delivery, prolonged labor), maternal diabetes [9] Infiltration of the adrenal glands Tumors (adrenocortical tumors, lymphomas, metastatic carcinoma) Amyloidosis Hemochromatosis Adrenalectomy Impaired activity of enzymes that are responsible for cortisol synthesis Cortisol synthesis inhibitors (e.g., rifampin, fluconazole, phenytoin, ketoconazole): drug-induced adrenal insufficiency 21-hydroxylase deficiency (see Congenital adrenal hyperplasia) Other causes Secondary adrenal insufficiency Secondary adrenal insufficiency is caused by conditions that decrease ACTH production (impaired hypothalamic-pituitary-adrenal axis)
Antipsychotic-associated weight gain and clinical improvement under clozapine treatment