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Mounjaro is excluded because it is a diabetes drug

Alcohol does not require digestion

This is why regulatory guidance emphasizes cautious NSAID use in patients on GLP-1 therapy

20,21 A systematic review and meta-analysis of randomised controlled trials evaluating weight-reduction diets with or without exercise reported an 18% reduction in premature mortality over a median trial duration of two years in adults with obesity

For instance, weight loss and improved insulin sensitivity may alter the bodys hormonal milieu, potentially affecting the metabolism and effectiveness of administered hormones like estrogen, progesterone, and testosterone

The clinical concern is not about drug testing but about gastroparesis risk: semaglutide slows gastric emptying, which can increase aspiration risk under general anesthesia if fasting protocols are not appropriately extended