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10.2399/jmu.2014001005 J Med Updates

However, gastrointestinal side effectsnausea, vomiting, diarrheacan occur with either medication, and combining them may increase the likelihood of mild to moderate digestive symptoms during the first few weeks of semaglutide initiation

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Common symptoms include reduced appetite, mild nausea, early satiety after small meals, and minor changes in bowel habits such as constipation or loose stools