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Specifically, after ligation, in the control rats, the brain damages are widespread, with increased edema and congestion, rapidly and particularly progressing as shown in the cerebral and cerebellar cortex, hypothalamus/thalamus, and hippocampus (Figure 9)

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Most peptide regimens used in obesity and metabolic research show good overall tolerability, but they still carry risks, particularly for patients with diabetes, cardiovascular disease, or cancer history

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