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doi: 10.3389/fcell.2025.1596421 Received 19 March 2025 Accepted 22 April 2025 Published 13 May 2025 Volume 13 - 2025 Edited by Matteo Avella, Sidra Medicine, Qatar Reviewed by Jurandy Penitente-Filho, JPF Consultoria, Brazil Qi Yin, Carnegie Institution for Science, United States Updates Copyright 2025 Gmez-Elas, Luque, Oscoz-Susino, Novero, Briski, Ksparas, Steeman, Stival, Lavolpe, Julianelli, Geller, Attie, Vassena, Krapf and Buffone

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FDA has received reports of consumers who have used fat-dissolving injections that are not FDA approved and that have caused adverse reactions (bad side effects)

Migraine involves interactions within the central and peripheral nervous systems, with significant activation and sensitization of the trigeminovascular system (TVS) in pain generation and transmission

Interdependence in cellular metabolism NAD+ and glutathione pathways work closely together through NADPH