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Compared with NRAS activating mutations at positions 12 and 13, NRAS Q61 mutations exert a stronger activating effect on the MAPK pathway since codon 61 is the catalytic residue for GTP hydrolysis and Q61 mutation impedes the return of RAS to an inactive GDP-bound state (92)

Remember that consistency is key, and the most effective approach combines multiple strategies rather than relying on any single intervention

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This practice introduces cross-contamination and stability risks

The Cell Biology of Mitochondrial Membrane Dynamics

Figure S9 shows that each component only minimally inhibited cell proliferation at 0800 g/mL, indicating that the system was highly biocompatible