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The main types include: Hemoglobin A (HbA) : This is the most common type in adults and carries most of the oxygen

Chakrapani H, Kalathur RC, Maciag AE, Citro ML, Ji X, Keefer LK, et al

2014;2014:bcr2014204322

For the summary outcomes, we computed the estimates of the random effects using restricted maximum likelihood to estimate the heterogeneity variance, since we assumed clinical variability between the studies