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Is it the benefits of a lifestyle intervention for people with risk factors like diabetes or obesity, or are these drugs doing something more for brain health

As an SGLT2 inhibitor, ertugliflozin carries the same warnings as others in the class, including the potential for elevations in LDL cholesterol, as well as an increased risk of ketoacidosis, acute kidney injury and renal failure, urosepsis and pyelonephritis, genital mycotic infections, lower-limb amputation, and severe hypotension

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[PubMed] Fernandez AM, Martinez-Rachadell L, Navarrete M, Pose-Utrilla J, Davila JC, Pignatelli J, Diaz-Pacheco S, Guerra-Cantera S, Viedma-Moreno E, Palenzuela R, Ruiz De Martin Esteban S, Mostany R, Garcia-Caceres C, Tschp M, Iglesias T, De Ceballos ML, Gutierrez A, Torres Aleman I (2022) Insulin regulates neurovascular coupling through astrocytes

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