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JAMA Netw Open 2023;6:e233398

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Wing RR, Lang W, Wadden TA, Safford M, Knowler WC, Bertoni AG, Hill JO, Brancati FL, Peters A, Wagenknecht L

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Recommendations and Contraindications These combination therapies are particularly suited for patients with type 2 diabetes who are struggling to achieve target glucose levels with oral medication alone or who require both a GLP-1 receptor agonist and insulin but prefer to avoid multiple daily injections