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[24] [26] Although cross-reactivity with sulfonamide antibiotics appears unlikely, precaution or complete avoidance of nonantibiotic sulfonamides in individuals whose previous reaction was serious and/or life-threatening or in those with multiple drug hypersensitivities may be prudent

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Tripp et al.3) first described these changes in 1981 in a school aged girl of PCD with cardiomyopathy and cardiac syncope

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