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Eur J Med Genet

A placebo-controlled 10-person study examined a four-week treatment with 0.5% Ectoin in the crow's feet area and found a significant anti-wrinkle effect (-19% mean wrinkle depth) in 100% of the participants

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Active constituents such as harpagoside provide neuroprotection, suggesting indirect benefits in neuroendocrine disturbances associated with thyroid dysfunction (146, 147)

Orthostatic hypotension is a watch-out, especially in older adults on multiple antihypertensives