The GLP-1 hormone is produced by specialized intestinal cells, primarily in the small intestine and colon, shortly after food enters the digestive tract
Published peer-reviewed research has established several mechanisms through which these medications support weight management: they help reduce appetite by acting on hunger signals in the brain, they slow gastric emptying which promotes a feeling of fullness after meals and they help regulate post-meal blood sugar responses
371 In a study examining the effects of GLP-1RA on osteoporosis induced by ovariectomy in aged rats, administering exendin-4 for 16 weeks prevented deterioration of the trabecular microarchitecture and increased bone strength
Reddit users frequently discuss the financial challenges of GLP-1s and worry what might happen with their progress if costs get in the way of treatment
Abbreviations DPP-4: Dipeptidylpeptidase-4 GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 HbA1C: Hemoglobin A1C HDL-C: High-density lipoprotein cholesterol LDL-C: Low-density lipoprotein cholesterol T2DM: Type 2 diabetes mellitus References Elrick H, Stimmler L, Hlad CJ, Arai Y
But the critical distinction is what lean mass actually means
