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After all, semaglutide is semaglutide

It included 8 RCTs (5 evaluating pioglitazone and 3 evaluating rosiglitazone) enrolling 516 patients with biopsy-proven NASH for a duration of 6 to 24 months

Regarding direct effects on blood glucose, the evidence is mixed and largely observational

The findings from this study suggest that there is a significant association between the prescription of semaglutide and the occurrence of NAION in patients with T2D and those who are overweight or obese

Joyce E, Lala A, Stevens SR et al (2016) Prevalence, profile, and prognosis of severe obesity in contemporary hospitalized heart failure trial populations

The decision should be based on established indications, with any anti-inflammatory benefits considered as potential additional advantages rather than the main treatment goal