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Once absorbed, glucosinolate-derived isothiocyanates (like sulforaphane) are promptly conjugated to glutathione by a class of phase II detoxification enzymes known as glutathione S -transferases (GSTs) in the liver, and then sequentially metabolized in the mercapturic acid pathway ( Figure 2 )

The clinical studies of acetylcysteine therapy have evaluated either treatment of preclinical toxic effects (based on the RumackMatthew nomogram) or therapy in patients with established hepatic failure

scramble: 6.6 0.6, n = 3

Endocrinology 117:13361340

Hypercoaguable state associated with active human herpesvirus-6 (HHV-6) viremia in patients with chronic fatigue syndrome

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