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The TF-Fe 3+ complex then binds to transferrin receptor 1 (TFR1) at the plasma membrane and is internalized through endocytosis [17]
However, their role has expanded significantly in recent years
Several cellular processes are involved in the pathogenesis of AIH, including liver metabolism, mitochondrial oxidative stress and dysfunction, sterile inflammation, endoplasmic reticulum stress, autophagy, and microcirculation dysfunction