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It presents this as the mechanism that prompted clinical curiosity about GLP-1 agonists during the transition, while noting perimenopause-specific trials remain limited

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High GLP-1 release following mealtimes can lead to: Insulin Release: GLP-1 signals to the pancreas to increase insulin release following a meal, which can balance blood sugar levels

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However, the journey from promising animal data to effective human therapies is fraught with substantial challenges that must be balanced against the initial optimism