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The next fourteen years were spent figuring out how much to give, how often, how long, what are the results, side effects and complications

Although the purpose of the study was not to conduct quantitative analyses, questionnaire data showed a trend towards reduction in PHQ-9, GAD-7 and EDE-Q scores (Table 1), which were clinically significant given that change scores of 5, 4 and 0.57 are considered the minimal clinically important differences in PHQ-9, GAD-7 and total EDE-Q scores respectively [38,39,40]

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Adequate levels of B-12 can help prevent nerve damage and support the body's ability to repair damaged nerves

Moreover, LRRK2 differs from other proteins associated with PD, and its overexpression can lead to an increase in both TH protein and dopamine levels 29

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