A 2012 review by Pickart and Margolina documented GHK-Cu's influence on over 4,000 human genes, predominantly affecting pathways related to tissue remodelling, anti-inflammatory response, and metabolic regulation
Aug 2020;16(4):755-763
10.3389/fdmed.2024.1464009 119 LiuY.ZengY.MiaoY.ChengX.DengS.HaoX.et al (2020)
Injectable GHK-Cu delivers the compound systemically, affecting collagen synthesis throughout the body including in deep dermal layers, connective tissue, joint structures, and internal organs
Immunofluorescence tissues were mounted with ProLong Gold (Life Technologies, Cat# P36934), while H&E and immunohistochemistry tissues were mounted with Permount mounting media (Fisher Scientific, Cat# SP15500) and coverslipped for imaging
In the skin, it inhibits an enzyme called tyrosinase, a key component for melanin production, the pigment that gives skin its color