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They are anecdotal

the principal pharmacological-interaction consideration is co-administration with exogenous melatonin or other pineal-axis-modifying agents, where the proposed mechanism overlaps and pharmacodynamic addition rather than subtraction would be expected

ConjuChem Phase 2, 2006 (NCT00267527, DAC version) Halted in HIV patients after a cardiac event

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De Vadder et al., 2014

SURMOUNT studied tirzepatide for weight management (NEJM 2022)