The change in pH of TSB and 1 PBS at different GSH concentrations was determined using a pH meter (Mettler-Toledo GmbH, Greifensee, Switzerland) calibrated with pH standards of 4.0 and 7.0 and the pH values of TSB and 1 PBS as a function of GSH concentration reported in Table 2
Studies have shown that exposure to EDCs, such as bisphenol A and phthalates, can disrupt normal immune function in the brain, leading to chronic or excessive neuroinflammation
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Therapeutic outcomes in PD models also highlight age dependency and formulation differences: younger animals consistently show greater neuroprotection, while older models exhibit attenuated responses
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