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Common short-term side effects may include: Temporary water retention or bloating Mild joint stiffness or tingling Flushed skin or warmth at injection site Slight headache or fatigue (especially when beginning use) Peptide secretagogues like Ipamorelin appear to exhibit fewer adverse effects than GH or GHRH analogs and are highly selective for the GH axis (Smith et al., Journal of Endocrinological Investigation )

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This case highlights that vitamin B12 deficiency can manifest primarily as deep sensory disturbance without typical upper motor neuron signs or radiological findings, particularly in older adults

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Instead, it is added mainly to support energy and help offset the fatigue that can accompany a sharp drop in food intake