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Thats why I recommend testing your ferritin levels before supplementing and retesting your levels within 1-3 months, to ensure that you are supplementing enough (but not too much!)

Though unlikely with typical product concentrations that fall within safe parameters, awareness of this risk remains important

Rasmussen MH, Hvidberg A, Juul A, Main KM, Gotfredsen A, Skakkebae NE, Hilsted J

However, with the current environments we live in and the poor quality and mass production of food, especially animal products at the moment, everyone is at risk of having below sufficient levels of Vitmain B12

This increase in extravasation of the Evans blue dye is a clear sign of tissue inflammation (39, 40)

Some people notice better rest within the first days of treatment, though this varies and should not be expected overnight