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Orforglipron shows typical GLP-1-related gastrointestinal effects and discontinuation due to gastrointestinal symptoms appears similar compared to oral semaglutide
![Structure of [ 3 H]liraglutide (top) and the GLP-1 receptor agonists](https://www.researchgate.net/profile/Inga-Bjornsdottir-2/publication/45650716/figure/fig2/AS:667822585806848@1536232720030/Structure-of-3-Hliraglutide-top-and-the-GLP-1-receptor-agonists-liraglutide-and.png)
