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Nielsen and Per Sauerberg

While native IGF-1 within physiological ranges appears safe, supraphysiological stimulation of IGF-1 receptor signaling through exogenous administration of potent analogs like IGF-1 DES could theoretically promote growth of existing pre-malignant or malignant cells, accelerate tumor progression, or support metastatic spread by enhancing cell survival and proliferation while inhibiting apoptosis

The involvement of the oral cavity is extremely rare [74]

First, prescribing diets characterized by severe caloric restriction and meal replacements no longer appears necessary to enhance adherence to caloric restriction and weight loss with the new medications for obesity

Discuss the pros and cons with your doctor

This is especially important if youre taking other blood sugar medications